Antia Laboratories Inc.

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Nesiritide Acetate


CAS Number: 114471-18-0

Molecular Weight: 3464.04

Molecules Formula: C143H244N50Os42S4

Sequence: Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-[Cys-Phe-Gly-Arg- Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-leu-Gly-Cys]- Lys-Val-Leu-Arg-Arg-His-OH

Appearance: White powder

Nesiritide (Natrecor) is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is the recombinant form of the 32 amino acid human B-type natriuretic peptide, which is normally produced by the ventricular myocardium. Nesiritide works to facilitate cardiovascular fluid homeostasis through counterregulation of the renin-angiotensin-aldoesterone system, stimulating cyclic guanosine monophosphate, leading to smooth muscle cell relaxation. In simpler terms, it promotes vasodilation, natriuresis, and diuresis.

Reference:

1. Hodgson, Barbara B., and Kizior, Robert J. Saunders Nursing Drug Handbook 2006. St. Louis, MO: Elsevier, Saunders, 2006.

2. Science or Fiction: Use of Nesiritide as a First-Line Agent? John A. Noviasky, Pharm.D., Michael Kelberman, M.D., Karen M. Whalen, B.S., Roy Guharoy, Pharm.D., William Darko, Pharm.D

The product is only for R&D purpose,not for human use.We will not take any responsibility for illegal use.

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