Antia Laboratories Inc.

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Ivacaftor (VX-770)


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CAN No.: 873054-44-5

Molecular Formula: C24H28N2O3

Molecular Weight: 392.49

Chemical Name: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-1,4-dihydro-4oxoquinoline-3-carboxamide

Ivacaftor is a small molecule drug that facilitates improved chloride transport by potentiating the open probability of the G551D‑CFTR channel. Ivacaftor (VX-770, Kalydeco) is a potentiator of cystic fibrosis transmembrane conductance regulator (CFTR) targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.


1. "News and Analysis, Ivacaftor" Pamela B Davis et al.: Nature Reviews Drug Discovery 11, 349-350 (May 2012). Full text

The product is only for R&D purpose,not for human use.We will not take any responsibility for illegal use.