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CAS Number: 1196109-52-0

Molecular Formula: C24H23F3N4O2

Molecular Weight: 456.46

Chemical Name:N-​3-​pyridinyl-​4-​[[3-​[[5-​(trifluoromethyl)-​2-​pyridinyl]oxy]phenyl]methyl]-​1-​piperidinecarboxamide

Biological Activity

Selective fatty acid amide hydrolase (FAAH) inhibitor (Ki = 0.23 μM). Reduces inflammatory pain via a cannabinoid receptor-dependent mechanism. Highly efficacious and selective in vivo. Displays no activity at FAAH-2 (IC50 >10 μM).


1. Booker et. al: British Journal of Pharmacology 2011 "The FAAH Inhibitor PF-3845 Acts in the Nervous System to Reverse Lipopolysaccharide-induced Tactile Allodynia in Mice." 

2. Ahn et. al: Chem.Biol. 16 411(2009) "Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain." 

The product is only for R&D purpose,not for human use.We will not take any responsibility for illegal use.