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Rivaroxaban (BAY 59-7939)

R02176

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CAS Number: 366789-02-8

Molecular Formula: C19H18ClN3O5S

Molecular Weight: 435.88

Synonyms: 5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxa

Reference:

1."Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor." Roehrig S, Straub A, Pohlmann J, et al. J. Med. Chem., 2005, 48 (19), pp 5900–590 Full text

2. "Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty". Eriksson BI, Borris LC, Friedman RJ, et al. N Engl J Med 2008;358:2765-75 Full text

3. "There appeared to be no clinically relevant interaction between rivaroxaban and naproxen in healthy subjects, although some individuals may be more sensitive to the combination."  D Kubitza et al.: Br J Clin Pharmacol 63(4) 469-476 Full text

 

 

 

The product is only for R&D purpose,not for human use.We will not take any responsibility for illegal use.

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